Mycoplasmosis of young animals: epizootology, diagnosis and treatment. Vestin use in cattle How to deal with an outbreak

The invention relates to veterinary medicine. The drug includes an etiotropic substance, an antibiotic of the tetracycline series (levotetrasulfin) and immunomodulators (Vestin, Alnorin). For the treatment of mycoplasmosis, animals are injected intramuscularly with levotetrasulfin at a dose of 0.4 ml/kg and allorin at a dose of 400 IU/kg 1 time in 15 days, or levotetrasulfin at a dose of 0.4 ml/kg and vestin 0.06 mg/kg 1 time per day. 15 days. The method allows to increase the efficiency of treatment of animals by reducing the duration of treatment, 2 zpf-ly, 1 table.

Claim

1. A method for the treatment of mycoplasmosis in animals, including the administration of an antibiotic of the tetracycline series, characterized in that animals are additionally injected with allorin at a dose of 400 IU/kg of body weight, and levotetrasulfin is used as an antibiotic of the tetracycline series, which is administered at a dose of 0.4 ml/kg of live body weight of the animal.2. Method for the treatment of animal mycoplasmosis according to claim 1, characterized in that the animals are administered levotetrasulfin and allnorin once every 15 days. The method according to any one of claims 1 and 2, characterized in that the animals are additionally injected with vestin at a dose of 0.06 microns/kg of body weight.

Mycoplasmosis of cattle, pigs: treatment, symptoms, prevention This infectious disease is one of the most dangerous and widespread in the Russian Federation. Most often, mycoplasmosis of cattle and pigs is diagnosed, however, pathology can also affect birds. The peculiarity of the disease is that its pathogens are microorganisms that lack a cell wall. Because of this feature, mycoplasmosis is poorly treated with traditional antibiotics of previous generations, and therefore requires the use of the latest effective drugs. The lack of timely veterinary intervention is fraught with the development of many complications, leading farms to large economic losses. Mortality can be 10-15% of the total number of sick individuals. Causes of animal mycoplasmosis In nature, there are more than 10 types of mycoplasmas - microorganisms similar to bacteria, but differing in structure. To the main reasons, disease-causing, include: violation of hygiene in the place where animals are kept; dampness, high humidity in the air; reduced immunity of individuals due to poor microclimate, nutrition; purchase of an infected individual with hidden clinical manifestations of the disease in the herd ( incubation period microorganisms reaches 27 days). Infection occurs by aerogenic means - by breathing. Juveniles are especially sensitive. Most often sick piglets aged 3 to 10 weeks. Mycoplasmosis of calves usually develops at 15-60 days of age. Symptoms of mycoplasmosis Among the common manifestations of the pathology are: inflammation, soreness of the knee and carpal joints with the formation of fistulas; lameness; redness of the eyes; apathy, lack of appetite; fever up to 40.1-40, 5 ° C; sneezing, mucous discharge from the nose; cough, shortness of breath (more often in piglets). In adult cows, the disease affects the udder, so the milk becomes yellow, its consistency becomes heterogeneous, and the volume of milk yield drops. Infection leads to numerous complications: in cows - mastitis, endometritis, vulvovaginitis, premature termination of pregnancy, the birth of underdeveloped offspring; in calves - arthritis, pneumonia, meningitis, rhinitis, conjunctivitis; in bulls - epididymitis, orchitis; in pigs - pneumonia, respiratory diseases. cows may develop infertility. Piglets with respiratory complications may die from suffocation. Diagnosis Diagnosis is based on physical examination, clinical manifestations and laboratory tests of tissues, secretions, aborted or stillborn fetuses. In the laboratory, the PCR method is used to detect the pathogen. Treatment of mycoplasmosis effective method treatment is the use of antibiotics. In mycoplasmosis, the latest generation drugs are used, since the microorganisms that cause mycoplasmosis develop resistance to traditional antibiotics. The NITA-FARM company suggests using Lexoflon, an antibiotic of the latest generation of fluoroquinolones, in the treatment of mycoplasmosis. It is based on levofloxacin, a substance related to third-generation fluoroquinolones. Treatment a wide range infections with resistance to antibiotics of the previous generation. The bioavailability of the drug is 99%. Within 2 hours after application, it reaches maximum efficiency, penetrating well into tissues. 100% effectiveness within 24-48 hours. It is equally effective in the treatment of mycoplasmosis of pigs and cattle. One daily injection is enough for a 3-5-day course. Within 2 days, it is completely excreted from the body, mainly with urine. Already 48 hours after the use of the drug, milk can be used for food purposes. Efficiency is confirmed by clinical studies and relevant documents. Lexoflon can be ordered directly from NITA-FARM. O complete diet to increase immunity; avoid stress factors in the form of increased humidity, temperature changes.

Mycoplasmosis of cattle is a contagious disease caused by mycoplasmas, microorganisms whose structure does not fit the description of viruses or bacteria. This disease is characterized by damage to the respiratory system, the development of pneumonia, keratoconjunctivitis, arthritis, endometritis, mastitis. The disease causes significant economic damage to the farm where it is registered, in the form of livestock deaths, loss of live weight and costs for treatment and preventive measures. It is important to understand what are the causes of the development of mycoplasmosis, how it manifests itself in cows, and how it is treated.

Causes

Infection with mycoplasmosis occurs in different ways - alimentary, airborne or intrauterine. Both adults and young animals can get sick. Sick animals or carriers of the pathogen excrete it into the external environment with saliva, urine, nasal mucus, milk, feces. The source of infection can be food, bedding, inventory. Often the carriers of pathogens are small rodents and insects.

Outbreaks of mycoplasmosis occur more often in autumn and winter when cows are kept in a stall. Favorable conditions for infection are:

Crowding of animals.
Dampness.
Poor diet, which leads to a decrease in the resistance of the body of cows.

Attention! To protect your farm from mycoplasma infection, it is important to quarantine all newly arrived animals on the farm for 30 days.

Symptoms

Mycoplasmas affect different systems of the animal body, so the symptoms in different forms of the disease are different. Most often, the pathogen affects the respiratory system. In this case, we are talking about respiratory mycoplasmosis. The symptoms of the disease are as follows:

General oppression.
Loss of appetite.
Sneezing, discharge from the nose, first clear mucous secretion, and later - purulent.
Dry cough that becomes loose over time.
Rapid breathing.
Wheezing.

If treatment is not started, the animal's condition gradually worsens. In the future, the development of polyarthritis is possible. Joints become inflamed, hot, painful. Sick animals are lame. Cows often develop mastitis. Mycoplasmosis can get worse bacterial infection, then the disease proceeds in an even more acute form and often ends in death.

In some calves, mycoplasmosis manifests itself as inflammation of the conjunctiva and cornea of the eyes. In this case, the symptoms of the disease are as follows:

Fear of the world.
Anxiety.
Tearing.
Redness of the cornea of the eyes, the appearance of gray and cloudy spots on it.

Attention! When inflammation from the conjunctival sac passes to the cornea, keratitis develops, while photophobia manifests itself even more acutely. As a result of the development of keratitis, blindness can occur.

Diagnostics

Diagnosis requires an integrated approach. When making a diagnosis, it is necessary to exclude infectious rhinotracheitis, adenovirus infection, as well as brucellosis, pasteurellosis, leptospirosis, chlamydia.

When making a diagnosis, not only the clinical signs of the disease are taken into account, but also the results of the pathoanatomical autopsy of animal corpses, as well as the results of laboratory research biomaterial. For analysis, material is taken from individuals who died from the disease, which did not receive treatment. It is important to take samples for research no later than 3-4 hours after death. Fragments are used as biomaterial internal organs- liver, brain, spleen, as well as the joints of dead cows.

Blood plasma, milk (with signs of mastitis), and nasal discharge are taken as material for testing for mycoplasmosis in living individuals. Using various methods in the samples taken for analysis, the presence of the causative agent of the disease is detected. The diagnosis is considered confirmed if the titers of antibodies to mycoplasma in the blood serum increase by more than 4 times.

Treatment

There is no specific treatment regimen for mycoplasmosis. Therapy is carried out in a complex and includes the use of:

antibiotics.
Expectorants.
vitamins.
Immunostimulants.

Attention! Diet is a must in treatment.

Antibiotics for cattle against mycoplasmosis are administered intramuscularly or orally. In the case of the spread of respiratory mycoplasmosis in the herd, it is advisable to use them in the form of aerosols for a whole group of sick animals. List of drugs used to combat mycoplasma:

Levomycetin;
Enroflon;
Tetracycline;
Tetravet;
Biomutin;
Tiamulin;
Dibiomycin;
Terravitin.

Reference. The course of antibiotic treatment is continued up to 7 days. The dosage is prescribed by the veterinarian.

An approximate treatment regimen for a group of calves infected with mycoplasmosis looks like this. Inside give Terravitin 500 at a dosage of 20-40 mg / kg in the morning and evening. In parallel, Trimerazine is given orally twice a day (dosage - 1 mg for every 15 kg of weight). The drug Biovit of prolonged action is given with food once a day, 3-5 g for each calf. Together with these drugs, it is necessary to introduce ascorbic acid 1 g per day into the treatment regimen.

Norsulfazole solution is administered intravenously. It is prepared like this:

600 ml of distilled water.
Glucose solution at a concentration of 40% - 300 ml.
Rectified alcohol 96% - 300 ml.
Norsulfazol in powder form - 40 g.

The prepared solution is administered once a day to each sick individual in a vein, 50 or 60 ml for 3 days. The next 4 days use a different solution for intravenous injection. It is administered to sick calves once a day, and is prepared from the following components:

Calcium chloride in the form of a solution at a concentration of 10% - 15 ml.
Glucose solution 40% - 25 ml.
Hexamethylenetetraamine solution 40% - 10 ml.
The fourth component is a solution of caffeine sodium benzoate (20%) - up to 3 ml.

To stimulate the discharge of sputum from the upper respiratory tract animals are given to drink mucolytics and expectorants. To enhance the body's resistance, the treatment regimen for mycoplasmosis includes B vitamins (mainly B12), as well as globulins or plant immunostimulants, such as eleutherococcus.

Important! To improve bowel function and restore microflora, it is desirable to give cows probiotics.

Prevention

To protect your livestock from mycoplasmosis, you must strictly adhere to the rules:

Never import animals to form a herd from farms that are considered unfavorable for mycoplasmosis. Do not accept inventory items from them.
When taking cows to the farm, keep them in quarantine for one month, carefully examine newly arrived individuals for signs of the development of the disease, paying special attention to the respiratory organs.
It is important to treat cowsheds from insects that can carry the pathogen of mycoplasmosis.
If rodents are found in the premises where livestock is kept, it is necessary to deratize.

If a case of infection with mycoplasmosis is registered on the farm, sick cows are separated into an isolation room and immediately begin treatment. All individuals that have been in contact with infected cows are treated antibacterial agents. Premises, inventory, bedding, feeders and drinkers are disinfected.

Attention! Milk from animals that have tested positive for mycoplasmosis requires heat treatment.

Mycoplasmosis of cattle is a dangerous infectious disease, but it can be fought. The treatment of this disease is most effective on initial stage Therefore, it is important to constantly monitor the health of animals on the farm. If signs of mycoplasmosis are found in a cow, it is necessary to report this fact to the veterinary service. The farm will be quarantined. It will be removed 2 months after the recovery of the last animal and the final disinfection.

Mycoplasmosis is one of the most common diseases in cattle, which in most cases leads to the death of the animal. Exists efficient scheme the fight against this disease, but the success of treatment depends entirely on the diagnosis of the disease on early stages. We will talk about the features of this disease and its treatment in the article today.

Mycoplasmosis - infectious disease cattle, caused by a single-celled bacterium, mycoplasma. Untimely treatment can bring significant economic damage - up to 15% of the herd die from mycoplasmosis. Important! Mastitis, endometritis, vulvovaginitis, salpingitis, abortion, infertility and the birth of premature and underdeveloped calves can bethe first signs of incipient mycoplasmosis.

Sources and routes of infection

Mycoplasmas are spread by airborne droplets. The main source of infection is a sick animal purchased for the farm. Often small rodents and insects become carriers of the disease.

There are a number of factors that contribute to the development of this disease:

high humidity in the calf;
poor diet;
weak immunity of livestock;
non-compliance with hygiene standards when caring for animals.

Symptoms and course of the disease

Mycoplasmosis has the following symptoms:

the cow's body temperature rises and keeps constantly at the level of + 40–41 ° С;
mucus begins to flow profusely from the nose, the animal often sneezes;
breathing becomes difficult, the cow has a cough;
the eyes of the animal turn red;
the individual becomes lethargic and refuses to eat;
milk yield drops significantly, milk becomes yellow and changes its consistency;
animals begin to limp due to inflammatory processes in the joints and wrists and the formation of fistulas there.

Diagnostics

To make a diagnosis, animals are examined, the clinical manifestations of the disease are studied. Important! Young individuals aged 15 to 60 days are especially vulnerable to the disease. Allocations and affected tissue areas are examined in the laboratory. Mycoplasmosis is detected on the basis of data obtained by polymer chain reaction (PCR).

How to treat

Comprehensive therapy to combat mycoplasmosis includes:

antibiotics;
immunostimulants;
expectorants;
vitamins.

Infectious diseases of cattle also include chlamydia, lumpy skin disease, brucellosis, udder warts, EMCAR, bluetongue, leptospirosis, malignant catarrhal fever, anaplasmosis, parainfluenza-3 and actinomycosis.

Antibiotics are used both intramuscularly and orally or in the form of aerosols. The latter are effective in mass infection of cattle.

In the fight against mycoplasmosis, the following drugs are used:

"Tetracycline";
"Levomitsetin";
"Tetravet";
"Enroflon";
"Biomutin";
"Dibiomycin".

To stimulate sputum discharge, expectorants and mucolytics must be included in the treatment regimen. You can increase the immunity of an animal with the help of B vitamins, globulins and plant immunostimulants, for example, eleutherococcus. Did you know? The harm from manure and intestinal gases of cows is many times greater than the damage caused to the environment by cars.

Prevention and vaccine against mycoplasmosis

Preventive measures to combat the disease consist of the following activities:

clear control over animals that are imported to form a herd;
refusal to cooperate with farms unfavorable for mycoplasmosis;
keeping cows admitted to the farm in quarantine for at least one month. During this time, it is necessary to examine the animals, paying special attention to the respiratory organs;
the barn should be subjected to regular deratization and treatment from insects;
when a case of infection is detected, the sick animal must be isolated, and all individuals that have been in contact with it must be treated with antibacterial agents;
if mycoplasmosis is detected, the barn, inventory, drinkers and feeders are disinfected;
creation of optimal conditions for keeping cattle.

Vaccination purely against mycoplasmosis in most cases does not lead to the desired result. For a complex vaccine that is effective in combating mycoplasma, it is better to consult a veterinarian. Did you know? Bulls do not distinguish colors. During a bullfight, it is not the red color that angers the bull, but the sharp movements of the bullfighter. Mycoplasmosis - dangerous disease Therefore, it is important to constantly monitor the condition of the herd and, at the first suspicion of its presence, contact the veterinary service. Timely diagnosis and proper treatment help to maintain the health of the livestock. And the maintenance and care of cows, organized in accordance with all the rules and requirements, will be the best preventive measures.

Mycoplasmosis is one of the most common diseases in cattle, which in most cases leads to the death of the animal. There is an effective scheme to combat this disease, but the success of treatment depends entirely on the diagnosis of the disease in the early stages. We will talk about the features of this disease and its treatment in the article today.

What is this disease

Mycoplasmosis is an infectious disease of cattle caused by the single-celled bacterium mycoplasma. Untimely treatment can bring significant economic damage - up to 15% of the herd die from mycoplasmosis.

Important! Mastitis, endometritis, vulvovaginitis, salpingitis, abortion, infertility and the birth of premature and underdeveloped calves can be the first signs of incipient mycoplasmosis.

Sources and routes of infection

Mycoplasmas are spread by airborne droplets. The main source of infection is a sick animal purchased for the farm. Often small rodents and insects become carriers of the disease.

There are a number of factors that contribute to the development of this disease:

high humidity in the calf;
poor diet;
weak immunity of livestock;
non-compliance with hygiene standards when caring for animals.

Symptoms and course of the disease

Mycoplasmosis has the following symptoms:

the cow's body temperature rises and keeps constantly at the level of + 40–41 ° С;
mucus begins to flow profusely from the nose, the animal often sneezes;
breathing becomes difficult, the cow has a cough;
the eyes of the animal turn red;
the individual becomes lethargic and refuses to eat;
milk yield drops significantly, milk becomes yellow and changes its consistency;
animals begin to limp due to inflammatory processes in the joints and wrists and the formation of fistulas there.

Diagnostics

To make a diagnosis, animals are examined, the clinical manifestations of the disease are studied.

Important! Young individuals aged 15 to 60 days are especially vulnerable to the disease.

Allocations and affected tissue areas are examined in the laboratory. Mycoplasmosis is detected on the basis of data obtained by polymer chain reaction (PCR).

How to treat

Comprehensive therapy to combat mycoplasmosis includes:

antibiotics;
immunostimulants;
expectorants;
vitamins.

Antibiotics are used both intramuscularly and orally or in the form of aerosols. The latter are effective in mass infection of cattle.

In the fight against mycoplasmosis, the following drugs are used:

"Tetracycline";
"Levomitsetin";
"Tetravet";
"Enroflon";
"Biomutin";
"Dibiomycin".

Did you know? The harm from manure and intestinal gases of cows is many times greater than the damage caused to the environment by cars.

Prevention and vaccine against mycoplasmosis

Preventive measures to combat the disease consist of the following activities:

clear control over animals that are imported to form a herd;
refusal to cooperate with farms unfavorable for mycoplasmosis;
keeping cows admitted to the farm in quarantine for at least one month. During this time, it is necessary to examine the animals, paying special attention to the respiratory organs;
the barn should be subjected to regular deratization and treatment from insects;
when a case of infection is detected, the sick animal must be isolated, and all individuals that have been in contact with it must be treated with antibacterial agents;
if mycoplasmosis is detected, the barn, inventory, drinkers and feeders are disinfected;
creation of optimal conditions for keeping cattle.

Vaccination purely against mycoplasmosis in most cases does not lead to the desired result. For a complex vaccine that is effective in combating mycoplasma, it is better to consult a veterinarian.